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Antibody used in WB on Human , Mouse cell lines.
Antibody used in WB on Human Jurkat 5.0 ug/ml.
Antibody used in WB on Human , Mouse cell lines.

M6PR Antibody

CATALOG NUMBER: 29-879

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human M6PR.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
M6PR antibody can be used for detection of M6PR by ELISA at 1:312500. M6PR antibody can be used for detection of M6PR by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
28 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store M6PR antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
M6PR
Additional Names:
M6PR, CD-MPR, FLJ32994, MPR46, SMPR, MPR 46, MPR-46
Protein Accession Number:
NP_002346
Protein Gi Number:
4505061
Ncbi Gene Id Number:
4074
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
Background Reference 1:
Chen, J.J., (2004) Cell 119 (7), 915-926.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-879

List Size:
100 ul

List Price:

$473.00

Datasheet
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