MAEA Antibody

CATALOG NUMBER: 59-522

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Zebrafish, Monkey, Mouse, Rat, Xenopus
Immunogen:
This MAEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-42 amino acids from the N-terminal region of human MAEA.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
45 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MAEA
Additional Names:
Macrophage erythroblast attacher, Cell proliferation-inducing gene 5 protein, Erythroblast macrophage protein, Human lung cancer oncogene 10 protein, HLC-10, MAEA, EMP
Protein Accession Number:
Q7L5Y9
Protein Gi Number:
74754297
Ncbi Gene Id Number:
10296
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene product mediates the attachment of erythroblaststo macrophages. This attachment promotes terminal maturation andenucleation of erythroblasts, presumably by suppressing apoptosis.This protein is an integral membrane protein with the N-terminus onthe extracellular side and the C-terminus on the cytoplasmic sideof the cell. Two immunologically related isoforms of erythroblastmacrophage protein with apparent molecular weights of 33 kD and 36kD were detected in macrophage membranes; this gene encodes thelarger isoform. Multiple alternatively spliced transcript variantsencoding distinct isoforms have been found for this gene, but thebiological validity of some variants has not been determined.
Background Reference 1:
Kobayashi, N., et al. Gene 396(2):236-247(2007)
Background Reference 2:
Bala, S., et al. Biochem. Biophys. Res. Commun. 342(4):1040-1048(2006)
Background Reference 3:
Hanspal, M., et al. Blood 92(8):2940-2950(1998)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-522

List Size:
400 ul

List Price:

$495.00

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