MAK Antibody

CATALOG NUMBER: 60-862

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This MAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 595-623 amino acids from the C-terminal region of human MAK.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
71 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MAK
Additional Names:
Serine/threonine-protein kinase MAK, Male germ cell-associated kinase, MAK
Protein Accession Number:
P20794
Protein Gi Number:
13432166
Ncbi Gene Id Number:
4117
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The product of this gene is a serine/threonine proteinkinase related to kinases involved in cell cycle regulation. It isexpressed almost exclusively in the testis, primarily in germcells. Studies of the mouse and rat homologs have localized thekinase to the chromosomes during meiosis in spermatogenesis,specifically to the synaptonemal complex that exists whilehomologous chromosomes are paired. There is, however, a study ofthe mouse homolog that has identified high levels of expression indeveloping sensory epithelia so its function may be moregeneralized.
Background Reference 1:
Fu, Z., et al. Mol. Cell. Biol. 26(22):8639-8654(2006)
Background Reference 2:
Ma, A.H., et al. Cancer Res. 66(17):8439-8447(2006)
Background Reference 3:
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Background Reference 4:
Xia, L., et al. J. Biol. Chem. 277(38):35422-35433(2002)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-862

List Size:
400 ul

List Price:

$495.00

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