Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

Western blot analysis of MALT1 in EL4 cell lysate with MALT1 antibody at (A) 1 and (2) μg/ml.
Immunohistochemistry of MALT1 in human spleen tissue with MALT1 antibody at 5 μg/mL.
Immunofluorescence of MALT1 in human spleen tissue with MALT1 antibody at 20 μg/mL.
Western blot analysis of MALT1 in EL4 cell lysate with MALT1 antibody at (A) 1 and (2) μg/ml.
Trial Size

MALT1 Antibody

CATALOG NUMBER: 8097

Clonality:
Polyclonal
Tested Applications:
ELISA, IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
MALT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MALT1.
The immunogen is located within amino acids 630 - 680 of MALT1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF, IHC-P, WB
Application Note:
MALT1 antibody can be used for detection of MALT1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificity:
MALT1 antibody is human, mouse and rat reactive. At least two isoforms of MALT1 are known to exist; this antibody will detect both isoforms.
Positive Control 1:
Cat. No. 1287 - EL4 Cell Lysate
Positive Control 2:
Cat. No. 10-901 - Human Spleen Tissue Slide
Predicted Molecular Weight:
Predicted: 91 kDa
Observed: 96 kDa
Purification:
MALT1 antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
MALT1 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
MALT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Ncbi Official Symbol:
MALT1
Additional Names:
Mucosa associated lymphoid tissue lymphoma translocation 1, IMD12, MLT, MLT1
Protein Accession Number:
NP_006776
Protein Gi Number:
5803078
Ncbi Gene Id Number:
10892
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
MALT1 was initially identified as a novel gene that was recurrently rearranged in t(11;18)(q21;q21) mucosa-associated lymphoid tissue lymphomas along with the apoptosis inhibitor protein c-IAP2 (1). MALT1, along with the proteins CARMA1 and Bcl10 form an NF-kappaB-activating complex, termed the CBM signalsome, that acts downstream of lymphocyte antigen receptors as well as many other non-lymphoid cell-surface receptors that play a role in multiple cellular functions (2,3). MALT1 has proteolytic activity, and this activity is critical for full NF-kappaB response in T cell activation (4).
Background Reference 1:
Dielamm J, Baens M, Wlodarska I, et al. The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas. Blood 1999; 93:3601-9.
Background Reference 2:
Lin X and Wang D. The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signaling. Semin. Immunol. 2004; 16:429-35.
Background Reference 3:
Rosebeck S, Rehman AO, Lucas PC, et al. From MALT lymphoma to the CBM signalsome: three decades of discovery. Cell Cycle 2011; 10:2485-96.
Background Reference 4:
Staal J, Bekaert T, and Beyaert R. Regulation of NF-kB signaling by caspases and MALT1 paracaspase. Cell Res. 21:40-54.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

8097

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369