MAML1 Antibody

CATALOG NUMBER: 55-913

Clonality:
Polyclonal
Tested Applications:
Flow, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MAML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-225 amino acids from the Central region of human MAML1.
Conjugate:
Unconjugated
Tested Applications:
Flow, WB
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
Predicted Molecular Weight:
108 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MAML1
Additional Names:
Mastermind-like protein 1, Mam-1, MAML1 (HGNC:13632)
Protein Accession Number:
Q92585
Protein Gi Number:
68565602
Ncbi Gene Id Number:
9794
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This protein is the human homolog of mastermind, aDrosophila protein that plays a role in the Notch signaling pathwayinvolved in cell-fate determination. There is in vitro evidencethat the human homolog forms a complex with the intracellularportion of human Notch receptors and can increase expression of aNotch-induced gene. This evidence supports its proposed function asa transcriptional co-activator in the Notch signaling pathway.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Lindberg, M.J., et al. FASEB J. 24(7):2396-2404(2010)
Background Reference 3:
Hao, L., et al. Oncogene 29(2):201-213(2010)
Background Reference 4:
Saint Just Ribeiro, M., et al. Curr. Protein Pept. Sci. 10(6):570-576(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-913

List Size:
400 ul

List Price:

$495.00

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