MAN2A1 Antibody

CATALOG NUMBER: 55-532

Clonality:
Polyclonal
Tested Applications:
Flow, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MAN2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-482 amino acids from the Central region of human MAN2A1.
Conjugate:
Unconjugated
Tested Applications:
Flow, WB
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
Predicted Molecular Weight:
131 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MAN2A1
Additional Names:
Alpha-mannosidase 2, Golgi alpha-mannosidase II, AMan II, Man II, Mannosidase alpha class 2A member 1, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN2A1, MANA2
Protein Accession Number:
Q16706
Protein Gi Number:
146345453
Ncbi Gene Id Number:
4124
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein which is a member of family 38of the glycosyl hydrolases. The protein is located in the Golgi andcatalyzes the final hydrolytic step in the asparagine-linkedoligosaccharide (N-glycan) maturation pathway. Mutations in themouse homolog of this gene have been shown to cause a systemicautoimmune disease similar to human systemic lupus erythematosus.
Background Reference 1:
Han, S., et al. Leuk. Res. 34(10):1271-1274(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Zhou, J.B., et al. Med. Sci. Monit. 16 (6), BR179-BR183 (2010) :
Background Reference 4:
Miyagawa, H., et al. Rheumatology (Oxford) 47(2):158-164(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-532

List Size:
400 ul

List Price:

$495.00

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