MAP3K1 (phospho Thr1402) Antibody

CATALOG NUMBER: 79-851

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
MAP3K1 (phospho Thr1402) antibody was raised against a peptide sequence around phosphorylation site of threonine 1402 (T-G-A (p)-G-F) derived from Human MAP3K1.
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
The antibody detects endogenous levels of MAP3K1 only when phosphorylated at threonine 1402.
Predicted Molecular Weight:
130 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
MAP3K1
Additional Names:
M3K1, MAP3K1, MAPKKK1, MEKK1
Protein Accession Number:
NP_005912.1
Protein Gi Number:
153945765
Ncbi Gene Id Number:
4214
Background:
Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.
Background Reference 1:
Schmutz J., Nature 431:268-274(2004).
Background Reference 2:
Xia Y., Genes Dev. 12:3369-3381(1998).
Background Reference 3:
Vinik B.S., Mamm. Genome 6:782-783(1995)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-851

List Size:
0.1 mg

List Price:

$376.00

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