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Western blot analysis of MAP3K11 Antibody in mouse lung tissue lysates (35ug/lane)
Western blot analysis of MAP3K11 Antibody in mouse lung tissue lysates (35ug/lane)

MAP3K11 Antibody

CATALOG NUMBER: 61-820

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This MAP3K11 antibody is generated from rabbits immunized with MAP3K11 recombinant protein.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
93 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MAP3K11
Additional Names:
Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11 (HGNC:6850)
Protein Accession Number:
Q16584
Protein Gi Number:
71153819
Ncbi Gene Id Number:
4296
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
MAP3K11 is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
Background Reference 1:
Rangasamy, V., et al. Cancer Res. 70(4):1731-1740(2010)
Background Reference 2:
Velho, S., et al. Hum. Mol. Genet. 19(4):697-706(2010)
Background Reference 3:
Cole, E.T., et al. Biochim. Biophys. Acta 1793(12):1811-1818(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-820

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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