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Antibody used in IHC on Human Liver.
Antibody used in WB on Human Jurkat cells at 0.2-1 ug/ml.
Antibody used in IHC on Human Liver.

MAPK14 Antibody

CATALOG NUMBER: 31-048

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAPK14.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
MAPK14 antibody can be used for detection of MAPK14 by ELISA at 1:62500. MAPK14 antibody can be used for detection of MAPK14 by western blot at 0.06 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1309 - Human Placenta Lysate
Predicted Molecular Weight:
41 kDa, 41 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store MAPK14 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
MAPK14
Additional Names:
MAPK14, RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA
Protein Accession Number:
NP_001306
Protein Gi Number:
4503069
Ncbi Gene Id Number:
1432
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
MAPK14 encodes a protein which is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Background Reference 1:
Aleman, M., et al., (2004) Infect. Immun. 72 (9), 5150-5158.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

31-048

List Size:
100 ul

List Price:

$519.00

Datasheet
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