MARCH1 Antibody

CATALOG NUMBER: 25-837

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MARCH1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
MARCH1 antibody can be used for detection of 40238 by ELISA at 1:1562500. MARCH1 antibody can be used for detection of 40238 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Predicted Molecular Weight:
31 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store MARCH1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
MARCH1
Additional Names:
MARCH1, DKFZp564M1682, FLJ20668, MARCH-I, RNF171
Protein Accession Number:
NP_060393
Protein Gi Number:
8923613
Ncbi Gene Id Number:
55016
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Background Reference 1:
De (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (9), 3491-3496.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-837

List Size:
100 ul

List Price:

$519.00

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