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Antibody used in WB on Human Brain at 0.2-1 ug/ml.
Antibody used in WB on Human Hela at 1 ug/ml.
Antibody used in WB on Hum. Fetal Brain at 1 ug/ml.
Antibody used in WB on Hum. Fetal Heart at 1 ug/ml.
Antibody used in WB on Human Brain at 0.2-1 ug/ml.

MBNL2 Antibody

CATALOG NUMBER: 30-736

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MBNL2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
MBNL2 antibody can be used for detection of MBNL2 by ELISA at 1:1562500. MBNL2 antibody can be used for detection of MBNL2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Predicted Molecular Weight:
28 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store MBNL2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
MBNL2
Additional Names:
MBNL2, DKFZp781H1296, MBLL, MBLL39, MGC120625, MGC120626, MGC120628, PRO2032, RP11-128N14.1
Protein Accession Number:
NP_005748
Protein Gi Number:
5031903
Ncbi Gene Id Number:
10150
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

30-736

List Size:
100 ul

List Price:

$519.00

Datasheet
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