Western blot analysis in WiDr cell line lysates (15ug/lane).

MC2R Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot analysis in WiDr cell line lysates (15ug/lane).

MC2R Antibody

CATALOG NUMBER: 61-968

Clonality:

Polyclonal

Tested Applications:

Flow, IHC-P, WB

Host Species:

Rabbit

Species Reactivity:

Human

Conjugate:

Unconjugated

Specifications

Host Species:

Rabbit

Species Reactivity:

Human

Homology:

Predicted species reactivity based on immunogen sequence: Mouse, Pig

Immunogen:

This MC2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-288 amino acids from the C-terminal region of human MC2R.

Conjugate:

Unconjugated

Tested Applications:

Flow, IHC-P, WB

Application Note:

For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50

Predicted Molecular Weight:

34 kDa

Advanced Validation

Properties

Purification:

This antibody is purified through a protein A column, followed by peptide affinity purification.

Clonality:

Polyclonal

Isotype:

Rabbit Ig

Physical State:

Liquid

Buffer:

Supplied in PBS with 0.09% (W/V) sodium azide.

Concentration:

batch dependent

Storage Conditions:

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

Ncbi Official Symbol:

MC2R

Additional Names:

Adrenocorticotropic hormone receptor, ACTH receptor, ACTH-R, Adrenocorticotropin receptor, Melanocortin receptor 2, MC2-R, MC2R, ACTHR

Protein Accession Number:

Q01718

Protein Gi Number:

399002

Ncbi Gene Id Number:

4158

User Note:

Optimal dilutions for each application to be determined by the researcher.

Background

Background:

MC2R encodes one member of the five-member G-proteinassociated melanocortin receptor family. Melanocortins(melanocyte-stimulating hormones and adrenocorticotropic hormone)are peptides derived from pro-opiomelanocortin (POMC). MC2R isselectively activated by adrenocorticotropic hormone, whereas theother four melanocortin receptors recognize a variety ofmelanocortin ligands.

Background Reference 1:

Holliday, K.L., et al. Ann. Rheum. Dis. 69(3):556-560(2010)

Background Reference 2:

Ding, Y.X., et al. Pharmacogenet. Genomics 20(2):71-76(2010)

Background Reference 3:

Roy, S., et al. Endocrinology 151(2):660-670(2010)

Citations

Set Contents

Disclaimer

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-968

List Size:

400 ul

List Price:

$495.00

Datasheet

Shipping Info

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$35 Dry Ice Shipment fee may be required on some items.

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MC2R Antibody

Clonality:

Tested Applications:

Host Species:

Species Reactivity:

Conjugate:

Host Species:

Species Reactivity:

Homology:

Immunogen:

Conjugate:

Tested Applications:

Application Note:

Predicted Molecular Weight:

Purification:

Clonality:

Isotype:

Physical State:

Buffer:

Concentration:

Storage Conditions:

Ncbi Official Symbol:

Additional Names:

Protein Accession Number:

Protein Gi Number:

Ncbi Gene Id Number:

User Note:

Background:

Background Reference 1:

Background Reference 2:

Background Reference 3:

Disclaimer:

List Size:

Shipping Info

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