MCC Antibody

CATALOG NUMBER: 59-060

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-501 amino acids from the Central region of human MCC.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
93 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MCC
Additional Names:
Colorectal mutant cancer protein, Protein MCC, MCC
Protein Accession Number:
P23508
Protein Gi Number:
317373352
Ncbi Gene Id Number:
4163
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a candidate colorectal tumor suppressor genethat is thought to negatively regulate cell cycle progression. Theorthologous gene in the mouse expresses a phosphoprotein associatedwith the plasma membrane and membrane organelles, andoverexpression of the mouse protein inhibits entry into S phase.Multiple transcript variants encoding different isoforms have beenfound for this gene.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Background Reference 3:
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Background Reference 4:
Arnaud, C., et al. FEBS Lett. 583(14):2326-2332(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-060

List Size:
400 ul

List Price:

$495.00

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