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Western blot analysis in Jurkat cell line lysates (35ug/lane).
MCOLN1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in Jurkat cell line lysates (35ug/lane).

MCOLN1 Antibody

CATALOG NUMBER: 57-113

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Mouse
Immunogen:
This MCOLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the C-terminal region of human MCOLN1.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
65 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MCOLN1
Additional Names:
Mucolipin-1, MG-2, Mucolipidin, MCOLN1, ML4
Protein Accession Number:
Q9GZU1
Protein Gi Number:
50401163
Ncbi Gene Id Number:
57192
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a memberof the transient receptorpotential (TRP) cation channel gene family. The transmembraneprotein localizes to intracellular vesicular membranes includinglysosomes, and functions in the late endocytic pathway and in theregulation of lysosomal exocytosis. The channel is permeable toCa(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changesin Ca(2+) concentration. Mutations in this gene result inmucolipidosis type IV.
Background Reference 1:
Eichelsdoerfer, J.L., et al. J. Biol. Chem. 285(45):34304-34308(2010)
Background Reference 2:
Curcio-Morelli, C., et al. J. Cell. Physiol. 222(2):328-335(2010)
Background Reference 3:
Vergarajauregui, S., et al. J. Biol. Chem. 284(52):36357-36366(2009)
Background Reference 4:
Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-113

List Size:
400 ul

List Price:

$495.00

Datasheet
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