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MDA5 Antibody [Hely-1]

CATALOG NUMBER: 36-114

Clonality:
Monoclonal
Tested Applications:
ELISA, IP, WB
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Immunogen:
Recombinant human MDA5 (aa 78-555).
Conjugate:
Unconjugated
Tested Applications:
ELISA, IP, WB
Application Note:
Immunoprecipitation: (1:100). Western Blot: (1:1‘000).
Specificity:
Recognizes human MDA5.
Purification:
>95% (SDS-PAGE)
Clonality:
Monoclonal
Isotype:
IgG1
physical-state:
Liquid
Buffer:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
IFIH1
Additional Names:
Helicard; Melanoma Differentiation-associated Gene 5
Protein Accession Number:
27886568
Protein Gi Number:
NP_071451
Ncbi Gene Id Number:
64135
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-114

List Size:
100 ug

List Price:

$540.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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