MEK1 (Ab 221) Antibody

CATALOG NUMBER: 79-349

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
MEK1 (Ab-221) antibody was raised against a peptide sequence around aa.219~223 (A-N-S-F-V) derived from Human MEK1.
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
This antibody detects endogenous level of total MEK1 protein.
Predicted Molecular Weight:
45 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
MAP2K1
Additional Names:
CFC3, MEK1, MKK1, MAPKK1, PRKMK1, JNKK1, MEK4, MKK4, PRKMK4, SEK1, SERK1, SKK1, ERK activator kinase 1, MAP kinase kinase 1, MAP2K1, MAPK/ERK kinase 1, MAPKK 1
Protein Accession Number:
NP_002746.1
Protein Gi Number:
5579478
Ncbi Gene Id Number:
5604
Background:
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.
Background Reference 1:
Zebisch A, et al. (2006) Cancer Res; 66 (7): 3401-8. Luciano BS, et al. (2006) J Biol Chem; 279 (50): 52117-23. Wang X, et al. (2003) Oncogene; 22 (1): 109-16. Gopalbhai K, et al. (2003) J Biol Chem; 278 (10): 8118-25. Ling MT, et al. (2002) Oncogene; 21 (55): 8498-505.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-349

List Size:
0.1 mg

List Price:

$370.00

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