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Antibody is used in Western blot to detect MRLK in mouse brain tissue lysate
Antibody is used in Western blot to detect MRLK in mouse brain tissue lysate

MELK Antibody

CATALOG NUMBER: 62-687

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MELK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human MELK.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
75 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MELK
Additional Names:
Maternal embryonic leucine zipper kinase, hMELK, Protein kinase Eg3, pEg3 kinase, Protein kinase PK38, hPK38, Tyrosine-protein kinase MELK, MELK, KIAA0175
Protein Accession Number:
Q14680
Protein Gi Number:
50400857
Ncbi Gene Id Number:
9833
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
MELK contains 1 protein kinase domain that belongs to the Ser/Thr protein kinase family. It phosphorylates ZNF622 and may contribute to its redirection to the nucleus. MELK may also be involved in the inhibition of spliceosome assembly during mitosis.
Background Reference 1:
Davezac, N., et al., Oncogene 21(50):7630-7641 (2002).
Background Reference 2:
Heyer, B.S., et al., Mol. Reprod. Dev. 47(2):148-156 (1997).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-687

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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