METTL3 Antibody

CATALOG NUMBER: 28-137

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human METTL3.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
METTL3 antibody can be used for detection of METTL3 by ELISA at 1:312500. METTL3 antibody can be used for detection of METTL3 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1207 - Raji Cell Lysate
Predicted Molecular Weight:
64 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store METTL3 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
METTL3
Additional Names:
METTL3, M6A, IME4, Spo8, MT-A70
Protein Accession Number:
NP_062826
Protein Gi Number:
21361827
Ncbi Gene Id Number:
56339
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
METTL3 is the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
Background Reference 1:
Bujnicki, J.M., et al., (2002) J. Mol. Evol. 55 (4), 431-444.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-137

List Size:
100 ul

List Price:

$473.00

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