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MIP-3 beta Recombinant Protein

CATALOG NUMBER: 40-354

Specifications
source-species:
E. coli
Species:
Murine
source-species:
E. coli
Recombinant Protein Sequence:
GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS
Biological Activity:
Determined by its ability to chemoattract activated human T cells expressing the CCR7 receptor. The ED50 for this effect is 30-90 ng/ml.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized MIP-3 beta recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted MIP-3 beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing MIP-3 beta recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
Ccl19
Additional Names:
ELC, CKb11, MIP3B, Scya19, exodus-3, Elc, C-C motif chemokine 19, Epstein-Barr virus-induced molecule 1 ligand chemokine, EBI1 ligand chemokine
Protein Accession Number:
NP_036018.1
Protein Gi Number:
6755422
Ncbi Gene Id Number:
24047
Background:
MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on murine cells. Recombinant murine MIP-3 beta is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-354

List Size:
0.005 mg, 0.02 mg

List Price:

Price range: $215.00 through $323.00

Datasheet
Shipping Info

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