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Western blot analysis in CEM cell line lysates (35ug/lane).
Western blot analysis in CEM cell line lysates (35ug/lane).

MKL1 Antibody

CATALOG NUMBER: 60-159

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MKL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 497-525 amino acids from the Central region of human MKL1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
99 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MKL1
Additional Names:
MKL/myocardin-like protein 1, Megakaryoblastic leukemia 1 protein, Megakaryocytic acute leukemia protein, Myocardin-related transcription factor A, MRTF-A, MKL1, KIAA1438, MAL
Protein Accession Number:
Q969V6
Protein Gi Number:
32363202
Ncbi Gene Id Number:
57591
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene interacts with thetranscription factor myocardin, a key regulator of smooth musclecell differentiation. The encoded protein is predominantly nuclearand may help transduce signals from the cytoskeleton to thenucleus. This gene is involved in a specific translocation eventthat creates a fusion of this gene and the RNA-binding motifprotein-15 gene. This translocation has been associated with acutemegakaryocytic leukemia.
Background Reference 1:
Gilles, L., et al. Blood 114(19):4221-4232(2009)
Background Reference 2:
Hinohara, K., et al. Hum. Genet. 126(4):539-547(2009)
Background Reference 3:
Estrada, K., et al. Hum. Mol. Genet. 18(18):3516-3524(2009)
Background Reference 4:
Brandt, D.T., et al. Nat. Cell Biol. 11(5):557-568(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-159

List Size:
400 ul

List Price:

$495.00

Datasheet
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