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Western blot analysis of lysates from K562, Ramos cell line (from left to right), using MLK4 Antibody at 1:1000 at each lane.
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with MLK4 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Western blot analysis of lysates from K562, Ramos cell line (from left to right), using MLK4 Antibody at 1:1000 at each lane.

MLK4 Antibody

CATALOG NUMBER: 63-334

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This MLK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human MLK4.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
114 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MLK4
Additional Names:
Mitogen-activated protein kinase kinase kinase MLK4, Mixed lineage kinase 4, MLK4 {ECO:0000303, Ref1}
Protein Accession Number:
Q5TCX8
Protein Gi Number:
71153820
Ncbi Gene Id Number:
84451
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Mixed-lineage kinases (MLKs) function as mitogen-activated protein kinase kinase kinases (MAP3Ks), activating the p38 and JNK signaling cascades. Systematic mutational analyses of tyrosine kinases reveal that a minimum of 30% of colorectal cancer contain at least one mutation in the tyrosine kinases; sampling of colorect cancer cells suggest an important role of MLK4 in this process.
Background Reference 1:
Gregory,S.G., Nature 441 (7091), 315-321 (2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-334

List Size:
400 ul

List Price:

$495.00

Datasheet
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