MLXIPL Antibody

CATALOG NUMBER: 56-508

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This MLXIPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 624-653 amino acids from the C-terminal region of human MLXIPL.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:2000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
93 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MLXIPL
Additional Names:
Carbohydrate-responsive element-binding protein, ChREBP, Class D basic helix-loop-helix protein 14, bHLHd14, MLX interactor, MLX-interacting protein-like, WS basic-helix-loop-helix leucine zipper protein, WS-bHLH, Williams-Beuren syndrome chromosomal region 14 protein, MLXIPL, BHLHD14, MIO, WBSCR14
Protein Accession Number:
Q9NP71
Protein Gi Number:
20140871
Ncbi Gene Id Number:
51085
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a basic helix-loop-helix leucine zippertranscription factor of the Myc/Max/Mad superfamily. This proteinforms a heterodimeric complex and binds and activates, in aglucose-dependent manner, carbohydrate response element (ChoRE)motifs in the promoters of triglyceride synthesis genes. The geneis deleted in Williams-Beuren syndrome, a multisystem developmentaldisorder caused by the deletion of contiguous genes at chromosome7q11.23.
Background Reference 1:
Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)
Background Reference 2:
Johansen, C.T., et al. Nat. Genet. 42(8):684-687(2010)
Background Reference 3:
Keebler, M.E., et al. Circ Cardiovasc Genet 3(4):358-364(2010)
Background Reference 4:
Chidambaram, M., et al. Metab. Clin. Exp. (2010) In press :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-508

List Size:
400 ul

List Price:

$495.00

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