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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

MMACHC Antibody

CATALOG NUMBER: 60-875

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MMACHC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the C-terminal region of human MMACHC.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
32 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MMACHC
Additional Names:
Methylmalonic aciduria and homocystinuria type C protein, MMACHC
Protein Accession Number:
Q9Y4U1
Protein Gi Number:
85681045
Ncbi Gene Id Number:
25974
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The exact function of the protein encoded by this gene isnot known, however, its C-terminal region shows similarity to TonB,a bacterial protein involved in energy transduction for cobalamin(vitamin B12) uptake. Hence, it is postulated that this protein mayhave a role in the binding and intracellular trafficking ofcobalamin. Mutations in this gene are associated with methylmalonicaciduria and homocystinuria type cblC.
Background Reference 1:
Froese, D.S., et al. Mol. Genet. Metab. 100(1):29-36(2010)
Background Reference 2:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 3:
Profitlich, L.E., et al. Mol. Genet. Metab. 98(4):344-348(2009)
Background Reference 4:
Kim, J., et al. J. Biol. Chem. 284(48):33418-33424(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-875

List Size:
400 ul

List Price:

$495.00

Datasheet
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