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Western blot analysis in LNCaP cell line lysates (35ug/lane).
MME Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in LNCaP cell line lysates (35ug/lane).

MME Antibody

CATALOG NUMBER: 55-080

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This MME antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 721-747 amino acids from the C-terminal region of human MME.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
86 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MME
Additional Names:
Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 2411, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN
Protein Accession Number:
P08473
Protein Gi Number:
128062
Ncbi Gene Id Number:
4311
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a common acute lymphocytic leukemiaantigen that is an important cell surface marker in the diagnosisof human acute lymphocytic leukemia (ALL). This protein is presenton leukemic cells of pre-B phenotype, which represent 85% of casesof ALL. This protein is not restricted to leukemic cells, however,and is found on a variety of normal tissues. It is a glycoproteinthat is particularly abundant in kidney, where it is present on thebrush border of proximal tubules and on glomerular epithelium. Theprotein is a neutral endopeptidase that cleaves peptides at theamino side of hydrophobic residues and inactivates several peptidehormones including glucagon, enkephalins, substance P, neurotensin,oxytocin, and bradykinin. This gene, which encodes a 100-kD type IItransmembrane glycoprotein, exists in a single copy of greater than45 kb. The 5' untranslated region of this gene is alternativelyspliced, resulting in four separate mRNA transcripts. The codingregion is not affected by alternative splicing. [provided byRefSeq].
Background Reference 1:
Wang, S., et al. J. Neurochem. 115(1):47-57(2010)
Background Reference 2:
Ikenaga, N., et al. Gastroenterology 139(3):1041-1051(2010)
Background Reference 3:
Kim, H.S., et al. Histopathology 56(6):708-719(2010)
Background Reference 4:
Toussaint, J., et al. PLoS ONE(8) (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-080

List Size:
400 ul

List Price:

$495.00

Datasheet
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