MOCS1 Antibody

CATALOG NUMBER: 60-344

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MOCS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-58 amino acids from the N-terminal region of human MOCS1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
70 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MOCS1
Additional Names:
Molybdenum cofactor biosynthesis protein 1, Cell migration-inducing gene 11 protein, Molybdenum cofactor synthesis-step 1 protein A-B, Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein A, Cyclic pyranopterin monophosphate synthase accessory protein, Molybdenum cofactor biosynthesis protein C, MOCS1
Protein Accession Number:
Q9NZB8
Protein Gi Number:
30913216
Ncbi Gene Id Number:
4337
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Molybdenum cofactor biosynthesis is a conserved pathwayleading to the biological activation of molybdenum. The proteinencoded by this gene is involved in this pathway. This gene wasoriginally thought to produce a bicistronic mRNA with the potentialto produce two proteins (MOCS1A and MOCS1B) from adjacent openreading frames. However, only the first open reading frame (MOCS1A)has been found to encode a protein from the putative bicistronicmRNA, whereas additional splice variants, whose full-length natureshave yet to be determined, are likely to produce a fusion betweenthe two open reading frames. This gene is defective in patientswith molybdenum cofactor deficiency, type A. A related pseudogenehas been identified on chromosome 16.
Background Reference 1:
Sass, J.O., et al. Brain Dev. (2009) In press :
Background Reference 2:
Arenas, M., et al. J. Inherit. Metab. Dis. 32(4):560-569(2009)
Background Reference 3:
Ichida, K., et al. Nucleosides Nucleotides Nucleic Acids 25 (9-11), 1087-1091 (2006) :
Background Reference 4:
Macaya, A., et al. Neuropediatrics 36(6):389-394(2005)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-344

List Size:
400 ul

List Price:

$495.00

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