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Western blot analysis in mouse kidney tissue lysates (35ug/lane).
Western blot analysis in mouse kidney tissue lysates (35ug/lane).

Mouse Acvr2a Antibody

CATALOG NUMBER: 58-133

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This Mouse Acvr2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-49 amino acids from the N-terminal region of mouse Acvr2a.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
58 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Acvr2a
Additional Names:
Activin receptor type-2A, Activin receptor type IIA, ACTR-IIA, Acvr2a, Acvr2
Protein Accession Number:
P27038
Ncbi Gene Id Number:
11480
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Background Reference 1:
Perron, J.C., et al. PLoS ONE(12), E8198 (2009) :
Background Reference 2:
Morita, S., et al. PLoS ONE(1), E4212 (2009) :
Background Reference 3:
Kamiya, N., et al. Development 135(22):3801-3811(2008)
Background Reference 4:
Xia, Y., et al. J. Biol. Chem. 282(25):18129-18140(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-133

List Size:
400 ul

List Price:

$495.00

Datasheet
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