Mouse CCL21/6Ckine Recombinant Protein (85-872)

CATALOG NUMBER: 85-872

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
Pichia
Species:
Mouse
source-species:
Pichia
Recombinant Protein Sequence:
Ser24-Gly133
Fusion Tag:
C-His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
12.89 kDa
Purity:
≥ 90 % as determined by SDS-PAGE.
Endotoxin:
< 0.1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.Contact us for customized product form or formulation.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
C-C Motif Chemokine 21a; 6Ckine; Beta-Chemokine Exodus-2; Small-Inducible Cytokine A21a;Thymus-Derived Chemotactic Agent 4; TCA4; Ccl21a; Scya21; Scya21a
Protein Accession Number:
P84444
Ncbi Gene Id Number:
18829
Background:
C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CCchemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signalpeptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms whileCCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 andCXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro forthymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 showspreferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes tosecondary lymphoid organs.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

85-872

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $140.00 through $350.00

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