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Western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Mdetected the Mouse Cdk14 protein (arrow).
Western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Mdetected the Mouse Cdk14 protein (arrow).

Mouse Cdk14 Antibody

CATALOG NUMBER: 60-536

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This Mouse Cdk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-72 amino acids from the N-terminal region of mouse Cdk14.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Cdk14
Additional Names:
Cyclin-dependent kinase 14, Cell division protein kinase 14, Serine/threonine-protein kinase PFTAIRE-1, Cdk14, Kiaa0834, Pftk1
Protein Accession Number:
O35495
Ncbi Gene Id Number:
18647
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity).
Background Reference 1:
Quina, L.A., et al. J. Neurosci. 29(45):14309-14322(2009)
Background Reference 2:
Jiang, M., et al. FEBS Lett. 583(13):2171-2178(2009)
Background Reference 3:
Jones, B.C., et al. Am. J. Physiol. Regul. Integr. Comp. Physiol. 293 (1), R116-R124 (2007) :
Background Reference 4:
Visel, A., et al. Nucleic Acids Res. 32 (DATABASE ISSUE), D552-D556 (2004) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-536

List Size:
400 ul

List Price:

$495.00

Datasheet
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