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Western blot analysis in mouse liver tissue lysates (35ug/lane).
Western blot analysis in mouse liver tissue lysates (35ug/lane).

Mouse Derl2 Antibody

CATALOG NUMBER: 60-461

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This Mouse Derl2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the C-terminal region of mouse Derl2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
28 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Derl2
Additional Names:
Derlin-2, Degradation in endoplasmic reticulum protein 2, Der1-like protein 2, F-LANa, Derl2, Der2, Flana
Protein Accession Number:
Q8BNI4
Ncbi Gene Id Number:
116891
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate (By similarity).
Background Reference 1:
Schaheen, B., et al. J. Cell. Sci. 122 (PT 13), 2228-2239 (2009) :
Background Reference 2:
Oda, Y., et al. J. Cell Biol. 172(3):383-393(2006)
Background Reference 3:
Lilley, B.N., et al. Proc. Natl. Acad. Sci. U.S.A. 102(40):14296-14301(2005)
Background Reference 4:
Kaput, J., et al. Physiol. Genomics 18(3):316-324(2004)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-461

List Size:
400 ul

List Price:

$495.00

Datasheet
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