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Recombinant Mouse E-Cadherin/CDH1/CD324 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Recombinant Mouse CDH1 measured by the ability of the immobilized protein to support the adhesion of the MCF-7 human breast cancer cells. The ED<sub>50</sub> for this effect is 0.82-3.29 μg/mL.
Recombinant Mouse E-Cadherin/CDH1/CD324 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Mouse E-Cadherin/CDH1/CD324 Recombinant Protein (85-740)

CATALOG NUMBER: 85-740

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Mouse
source-species:
HEK293 cells
Recombinant Protein Sequence:
Asp157-Val709
Fusion Tag:
C-6His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
61.70 kDa
Biological Activity:
Measured by the ability of the immobilized protein to support the adhesion of the MCF-7 human breast cancer cells. The ED50 for this effect is 0.82-3.29 μg/mL.
Purity:
≥ 95 % as determined by SDS-PAGE.
Endotoxin:
< 0.1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
Um; UVO; Ecad; ARC-1; E-cad; L-CAM;CDH1
Protein Accession Number:
NP_033994.1
Ncbi Gene Id Number:
12550
Background:
This protein is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

85-740

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $126.00 through $280.00

Datasheet
Shipping Info

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