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Western Blot at 1:1000 dilution + mouse lung lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution + mouse lung lysate Lysates/proteins at 20 ug per lane.

Mouse Epha2 Antibody

CATALOG NUMBER: 57-864

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This Mouse Epha2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-323 amino acids from the Central region of mouse Epha2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
109 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Epha2
Additional Names:
Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, Tyrosine-protein kinase receptor MPK-5, Tyrosine-protein kinase receptor SEK-2, Epha2, Eck, Myk2, Sek2
Protein Accession Number:
Q03145
Ncbi Gene Id Number:
13836
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Induces apoptosis in a TP53/p53-independent, caspase-8-dependent manner (By similarity). Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. May be involved in cell-cell interactions guiding early hindbrain development.
Background Reference 1:
Islam, S., et al. Dig. Dis. Sci. 55(9):2478-2488(2010)
Background Reference 2:
Kim, J., et al. Mol. Cell. Biol. 30(7):1582-1592(2010)
Background Reference 3:
Zirzow, S., et al. Dev. Biol. 336(2):145-155(2009)
Background Reference 4:
Jun, G., et al. PLoS Genet.(7), E1000584 (2009) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-864

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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