Mouse IL-1 alpha Recombinant Protein (85-991)

CATALOG NUMBER: 85-991

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
E. coli
Species:
Mouse
source-species:
E. coli
Recombinant Protein Sequence:
Ser115-Ser270
Fusion Tag:
NO-Tag
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
17.99 kDa
Biological Activity:
Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 for this effect is 3.075-12.3 pg/mL, corresponding to a specific activity of 8.13×107~3.25×108 units/mg.
Purity:
≥ 95 % as determined by SDS-PAGE;≥ 95 % as determined by HPLC.
physical-state:
Lyophilized
Buffer:
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
Il1a , Interleukin-1 alpha, IL-1 alpha
Protein Accession Number:
P01582
Ncbi Gene Id Number:
16175
Background:
Interleukin 1 alpha (IL-1α) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene. IL-1α is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

85-991

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $140.00 through $350.00

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