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Mouse IL-2 (C160S) Recombinant Protein (85-138)

CATALOG NUMBER: 85-138

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
E. coli
Species:
Mouse
source-species:
E. coli
Recombinant Protein Sequence:
Ala21-Gln169
Fusion Tag:
No-Tag
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
17.28 kDa
Biological Activity:
Measured in a cell proliferation assay using murine CTLL-2 cells. The ED50 for this effect is 0.49-1.98 ng/mL, corresponding to a specific activity of 5.05×105~2.02×106 units/mg.
Purity:
≥90 % as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
Il2, Il-2,Interleukin-2, IL-2, T-cell growth factor, TCGF
Protein Accession Number:
NP_032392.1
Ncbi Gene Id Number:
16183
Background:
Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared bycytokine receptors of all members of cytokine family. Mature mouse IL -2 shares 56% and 73% aa sequenceidentity with human and rat IL-2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, Bcells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance andimmunity, primarily via its potent stimulatory activity for T cells.Thus, IL-2 may be a key cytokine in the naturalsuppression of autoimmunity.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

85-138

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $126.00 through $280.00

Datasheet
Shipping Info

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