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Mouse LAG-3/CD223 Recombinant Protein (85-390)

CATALOG NUMBER: 85-390

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Mouse
source-species:
HEK293 cells
Recombinant Protein Sequence:
Gly24-Leu442
Fusion Tag:
C-His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
46.18 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA.Immobilized Mouse LAG3 at 1 μg/mL (100 μL/well) can bind LAG3 Rabbit pAb with a linear range of 0.06-1.2ng/mL.
Purity:
≥ 95 % as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
LAG3,CD223,FDC,Ly66,LAG3
Protein Accession Number:
NP_032505.1
Ncbi Gene Id Number:
16768
Background:
LAG3 (Lymphocyte Activating 3), also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily, is a protein-coding gene. 2 alternatively spliced human isoforms have been reported. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling, leading to increased antigen-specific T-cell responses in vivo. Diseases associated with LAG3 include Smoldering Myeloma and Kyphoscoliotic Heart Disease.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

85-390

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $126.00 through $280.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

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