Mouse Map3k14 Antibody

CATALOG NUMBER: 57-519

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This Mouse Map3k14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 652-680 amino acids from the C-terminal region of mouse Map3k14.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
103 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Map3k14
Additional Names:
Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, Serine/threonine-protein kinase NIK, Map3k14, Nik
Protein Accession Number:
Q9WUL6
Ncbi Gene Id Number:
53859
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
Background Reference 1:
Bhattacharyya, S., et al. Exp. Cell Res. 316(19):3317-3327(2010)
Background Reference 2:
Maeda, Y., et al. Int. Immunol. 22(6):515-525(2010)
Background Reference 3:
Sanjo, H., et al. J. Biol. Chem. 285(22):17148-17155(2010)
Background Reference 4:
Takeshima, T., et al. Cancer Res. 70(7):2697-2706(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-519

List Size:
400 ul

List Price:

$495.00

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