Mouse Pan3 Antibody

CATALOG NUMBER: 57-362

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This Mouse Pan3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 727-755 amino acids from the C-terminal region of mouse Pan3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
90 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Pan3
Additional Names:
PAB-dependent poly(A)-specific ribonuclease subunit PAN3 {ECO:0000255, HAMAP-Rule:MF_03181}, PAB1P-dependent poly(A)-nuclease {ECO:0000255, HAMAP-Rule:MF_03181}, PAN deadenylation complex subunit 3 {ECO:0000255, HAMAP-Rule:MF_03181}, Pan3
Protein Accession Number:
Q640Q5
Ncbi Gene Id Number:
72587
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, recruits polyadenylate-binding protein which in turn stimulates PAN2 nuclease activity (By similarity).
Background Reference 1:
Zheng, D., et al. J. Cell Biol. 182(1):89-101(2008)
Background Reference 2:
Siddiqui, N., et al. J. Biol. Chem. 282(34):25067-25075(2007)
Background Reference 3:
Nishimura, M., et al. DNA Res. 11(5):315-323(2004)
Background Reference 4:
Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-362

List Size:
400 ul

List Price:

$495.00

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