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Western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the Prkaca/Prkacb antibody detected the Prkaca/Prkacb protein (arrow).
Western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Prkaca/Prkacb antibody detected the Prkaca/Prkacb protein (arrow).
Mouse Prkaca/Prkacb Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Prkaca/Prkacb Antibody for immunohistochemistry.
Western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the Prkaca/Prkacb antibody detected the Prkaca/Prkacb protein (arrow).

Mouse Prkaca/Prkacb Antibody

CATALOG NUMBER: 57-746

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Pig, Rat
Immunogen:
This Mouse Prkaca/Prkacb antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-319 amino acids from the C-terminal region of mouse Prkaca/Prkacb.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
41 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Prkacb
Additional Names:
cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta, Prkacb, Pkacb
Protein Accession Number:
P68181
Ncbi Gene Id Number:
18749
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.
Background Reference 1:
Ribeiro, R.A., et al. Br. J. Nutr. 104(8):1148-1155(2010)
Background Reference 2:
Liu, J.X., et al. Seizure 19(7):414-420(2010)
Background Reference 3:
Ha, C.H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(35):15467-15472(2010)
Background Reference 4:
Sarma, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(29):13165-13170(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-746

List Size:
400 ul

List Price:

$495.00

Datasheet
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