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Mouse/Rat Mature TGF-beta 1 Recombinant Protein (85-112)

CATALOG NUMBER: 85-112

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Mouse
source-species:
HEK293 cells
Recombinant Protein Sequence:
Ala279-Ser390
Fusion Tag:
No tag
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
12.81 kDa
Biological Activity:
Measured by its ability to inhibit the IL-4-dependent proliferation of HT-2 Mouse T cells. The ED50 for this effect is 0.054-0.214 ng/mL, corresponding to a specific activity of 4.7×106~1.85×107 units/mg.
Purity:
≥ 95 % as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.2 μm filtered solution of 50 mM Glycine,150 mM NaCl, pH3.5. Contact us for customized product form or formulation.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
TGF-beta1,Tgfb,Tgfb-1,TGFbeta1,CED,DPD1,LAP,TGFB,TGFbeta,TGFB1
Protein Accession Number:
P04202
Ncbi Gene Id Number:
21803
Background:
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factorsand plays a prominent role in a variety of cellular processes, including cell-cycle progression, celldifferentiation,reproductivefunction,development,motility,adhesion,neuronalgrowth,bonemorphogenesis, wound healing, and immune surveillance. TGF- β 1, TGF- β 2 and TGF- β 3 signal via the sameheteromeric receptor complex, consisting of a ligand binding TGF- β receptor type II (T β R-II), and a TGF- βreceptor type I (T β R-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF- βexpression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney,gut, liver, eye, ear, skin, and the nervous system.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

85-112

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $210.00 through $490.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

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