Mouse Sgk1 Antibody

CATALOG NUMBER: 60-192

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Rat
Immunogen:
This Mouse Sgk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-352 amino acids from the C-terminal region of mouse Sgk1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
49 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Sgk1
Additional Names:
Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1, Sgk1, Sgk
Protein Accession Number:
Q9WVC6
Ncbi Gene Id Number:
20393
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a serine/threonine protein kinase thatplays an important role in cellular stress response. This kinaseactivates certain potassium, sodium, and chloride channels,suggesting an involvement in the regulation of processes such ascell survival, neuronal excitability, and renal sodium excretion.This enzyme is activated by protein phosphorylation and degradedvia the ubiquitination and proteasome pathway. Multiple transcriptvariants encoding different isoforms have been found for this gene.A pseudogene of this gene was identified on chromosome 12.
Background Reference 1:
Gao, D., et al. Mol. Cell 39(5):797-808(2010)
Background Reference 2:
Catela, C., et al. Dev. Dyn. 239(8):2149-2160(2010)
Background Reference 3:
Hallows, K.R., et al. J. Biol. Chem. 285(28):21671-21678(2010)
Background Reference 4:
Kaji, T., et al. Front Biosci (Elite Ed) 2, 1355-1361 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-192

List Size:
400 ul

List Price:

$495.00

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