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Western blot analysis of lysate from mouse liver tissue lysate, using Mouse Shb Antibody at 1:1000 at each lane.
Western blot analysis of lysate from mouse liver tissue lysate, using Mouse Shb Antibody at 1:1000 at each lane.

Mouse Shb Antibody

CATALOG NUMBER: 60-411

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Human
Immunogen:
This Mouse Shb antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-95 amino acids from the C-terminal region of mouse Shb.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
55 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Shb
Additional Names:
SH2 domain-containing adapter protein B, Shb
Protein Accession Number:
Q6PD21
Ncbi Gene Id Number:
230126
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells (By similarity).
Background Reference 1:
Calounova, G., et al. PLoS ONE(6), E11155 (2010) :
Background Reference 2:
Akerblom, B., et al. J. Endocrinol. 203(2):271-279(2009)
Background Reference 3:
Mokhtari, D., et al. Biochem. Biophys. Res. Commun. 387(3):553-557(2009)
Background Reference 4:
Funa, N.S., et al. Cancer Res. 69(5):2141-2148(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-411

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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