Mouse Taok2 Antibody

CATALOG NUMBER: 57-753

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This Mouse Taok2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the Central region of mouse Taok2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
139 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Taok2
Additional Names:
Serine/threonine-protein kinase TAO2, Thousand and one amino acid protein 2, Taok2, Kiaa0881
Protein Accession Number:
Q6ZQ29
Ncbi Gene Id Number:
381921
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Taok2 may play a role in apoptotic morphological changes. May affect microtubule organization and stability. May play a role in the osmotic stress-MAPK8 pathway. Activates the JNK MAP kinase pathway through the specific activation of the upstream MKK3 and MKK6 kinases. Prevents MAP3K7-mediated activation of IKKA, and thus NF-kappa-B activation. Phosphorylates itself, MBP, activated MAPK8 and tubulins (By similarity).
Background Reference 1:
Blackshaw, S., et al. PLoS Biol.(9), E247 (2004) :
Background Reference 2:
Thuret, S., et al. Mol. Cell. Neurosci. 25(3):394-405(2004)
Background Reference 3:
Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)
Background Reference 4:
Okazaki, N., et al. DNA Res. 10(4):167-180(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-753

List Size:
400 ul

List Price:

$495.00

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