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Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).
Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).

Mouse Tlk1 Antibody

CATALOG NUMBER: 59-114

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Human
Immunogen:
This Mouse Tlk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-728 amino acids from the C-terminal region of mouse Tlk1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
87 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Tlk1
Additional Names:
Serine/threonine-protein kinase tousled-like 1, Tousled-like kinase 1, Tlk1
Protein Accession Number:
Q8C0V0
Ncbi Gene Id Number:
228012
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly (By similarity). Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10' (By similarity).
Background Reference 1:
Canfield, C., et al. BMC Mol. Biol. 10, 110 (2009) :
Background Reference 2:
Taniwaki, T., et al. Dev. Growth Differ. 47(3):163-172(2005)
Background Reference 3:
Sunavala-Dossabhoy, G., et al. BMC Mol. Biol. 6, 19 (2005) :
Background Reference 4:
Cobellis, G., et al. Nucleic Acids Res. 33 (4), E44 (2005) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-114

List Size:
400 ul

List Price:

$495.00

Datasheet
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