MRI1 Antibody

CATALOG NUMBER: 61-260

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MRI1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-141 amino acids from the Central region of human MRI1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:8000
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MRI1
Additional Names:
Methylthioribose-1-phosphate isomerase {ECO:0000255, HAMAP-Rule:MF_03119}, M1Pi {ECO:0000255, HAMAP-Rule:MF_03119}, MTR-1-P isomerase {ECO:0000255, HAMAP-Rule:MF_03119}, 5.3.1.23 {ECO:0000255, HAMAP-Rule:MF_03119}, Mediator of RhoA-dependent invasion, S-methyl-5-thioribose-1-phosphate isomerase {ECO:0000255, HAMAP-Rule:MF_03119}, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein {ECO:0000255, HAMAP-Rule:MF_03119}, MRI1 {ECO:0000255, HAMAP-Rule:MF_03119}, MRDI
Protein Accession Number:
Q9BV20
Protein Gi Number:
74733279
Ncbi Gene Id Number:
84245
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
Background Reference 1:
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Background Reference 2:
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Background Reference 3:
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Background Reference 4:
Kabuyama Y.,et al.Mol. Cell. Proteomics 8:2308-2320(2009).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-260

List Size:
200 ul

List Price:

$495.00

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