MRPL2 Antibody

CATALOG NUMBER: 59-076

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This MRPL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 amino acids from the C-terminal region of human MRPL2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
33 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MRPL2
Additional Names:
39S ribosomal protein L2, mitochondrial, L2mt, MRP-L2, MRPL2
Protein Accession Number:
Q5T653
Protein Gi Number:
118573672
Ncbi Gene Id Number:
51069
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Mammalian mitochondrial ribosomal proteins are encoded bynuclear genes and help in protein synthesis within themitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of asmall 28S subunit and a large 39S subunit. They have an estimated75% protein to rRNA composition compared to prokaryotic ribosomes,where this ratio is reversed. Another difference between mammalianmitoribosomes and prokaryotic ribosomes is that the latter containa 5S rRNA. Among different species, the proteins comprising themitoribosome differ greatly in sequence, and sometimes inbiochemical properties, which prevents easy recognition by sequencehomology. This gene encodes a 39S subunit protein that belongs tothe EcoL2 ribosomal protein family. A pseudogene corresponding tothis gene is found on chromosome 12q.
Background Reference 1:
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Background Reference 2:
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Background Reference 3:
Zhang, Z., et al. Genomics 81(5):468-480(2003)
Background Reference 4:
Kenmochi, N., et al. Genomics 77 (1-2), 65-70 (2001) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-076

List Size:
400 ul

List Price:

$495.00

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