MRPL39 Antibody

CATALOG NUMBER: 58-835

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MRPL39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-330 amino acids from the C-terminal region of human MRPL39.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MRPL39
Additional Names:
39S ribosomal protein L39, mitochondrial, L39mt, MRP-L39, 39S ribosomal protein L5, mitochondrial, L5mt, MRP-L5, MRPL39, C21orf92, MRPL5, RPML5
Protein Accession Number:
Q9NYK5
Protein Gi Number:
296452977
Ncbi Gene Id Number:
54148
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Mammalian mitochondrial ribosomal proteins are encoded bynuclear genes and help in protein synthesis within themitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of asmall 28S subunit and a large 39S subunit. They have an estimated75% protein to rRNA composition compared to prokaryotic ribosomes,where this ratio is reversed. Another difference between mammalianmitoribosomes and prokaryotic ribosomes is that the latter containa 5S rRNA. Among different species, the proteins comprising themitoribosome differ greatly in sequence, and sometimes inbiochemical properties, which prevents easy recognition by sequencehomology. This gene encodes a 39S subunit protein. Two transcriptvariants encoding distinct isoforms have been described. Apseudogene corresponding to this gene is found on chromosome 5q.
Background Reference 1:
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Background Reference 2:
Zhang, Z., et al. Genomics 81(5):468-480(2003)
Background Reference 3:
O'Brien, T.W. Gene 286(1):73-79(2002)
Background Reference 4:
Kenmochi, N., et al. Genomics 77 (1-2), 65-70 (2001) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-835

List Size:
400 ul

List Price:

$495.00

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