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Western blot analysis in HL-60 cell line lysates (35ug/lane).
Western blot analysis in HL-60 cell line lysates (35ug/lane).

MSH5 Antibody

CATALOG NUMBER: 58-814

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MSH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 525-552 amino acids from the Central region of human MSH5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
93 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MSH5
Additional Names:
MutS protein homolog 5, hMSH5, MSH5
Protein Accession Number:
O43196
Ncbi Gene Id Number:
4439
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the mutS family of proteinsthat are involved in DNA mismatch repair and meiotic recombination.This protein is similar to a Saccharomyces cerevisiae protein thatparticipates in segregation fidelity and crossing-over eventsduring meiosis. This protein plays a role in promoting ionizingradiation-induced apoptosis. This protein forms heterooligomerswith another member of this family, mutS homolog 4. Polymorphismsin this gene have been linked to various human diseases, includingIgA deficiency, common variable immunodeficiency, and prematureovarian failure. Alternative splicing results multiple transcriptvariants.
Background Reference 1:
Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
Background Reference 2:
Pozo, N.D., et al. Hum. Immunol. 71(9):861-864(2010)
Background Reference 3:
Snowden, T., et al. J. Biol. Chem. 283(1):145-154(2008)
Background Reference 4:
Sekine, H., et al. Proc. Natl. Acad. Sci. U.S.A. 104(17):7193-7198(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-814

List Size:
400 ul

List Price:

$495.00

Datasheet
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