MSL3 Antibody

CATALOG NUMBER: 59-418

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This MSL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the N-terminal region of human MSL3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MSL3
Additional Names:
Male-specific lethal 3 homolog, Male-specific lethal-3 homolog 1, Male-specific lethal-3 protein-like 1, MSL3-like 1, MSL3, MSL3L1
Protein Accession Number:
Q8N5Y2
Protein Gi Number:
32171482
Ncbi Gene Id Number:
10943
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a nuclear protein that is similar to theproduct of the Drosophila male-specific lethal-3 gene. TheDrosophila protein plays a critical role in a dosage-compensationpathway, which equalizes X-linked gene expression in males andfemales. Thus, the human protein is thought to play a similarfunction in chromatin remodeling and transcriptional regulation,and it has been found as part of a complex that is responsible forhistone H4 lysine-16 acetylation. This gene can undergo Xinactivation. Alternative splicing results in multiple transcriptvariants. Related pseudogenes have been identified on chromosomes2, 7 and 8.
Background Reference 1:
Smith, E.R., et al. Mol. Cell. Biol. 25(21):9175-9188(2005)
Background Reference 2:
Marin, I., et al. Mol. Biol. Evol. 17(8):1240-1250(2000)
Background Reference 3:
Prakash, S.K., et al. Genomics 59(1):77-84(1999)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-418

List Size:
400 ul

List Price:

$495.00

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