Msx2 Antibody

CATALOG NUMBER: 61-435

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This Msx2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-222 amino acids from the C-terminal region of human Msx2.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
29 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MSX2
Additional Names:
Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8
Protein Accession Number:
P35548
Protein Gi Number:
311033429
Ncbi Gene Id Number:
4488
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
Background Reference 1:
Shao,J.S., Ann. N. Y. Acad. Sci. 1117, 40-50 (2007)
Background Reference 2:
Han,J., Mech. Dev. 124 (9-10), 729-745 (2007)
Background Reference 3:
Ghassibe,M., Eur. J. Pediatr. 165 (10), 734-735 (2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-435

List Size:
400 ul

List Price:

$495.00

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