MTIF2 Antibody

CATALOG NUMBER: 58-834

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This MTIF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the N-terminal region of human MTIF2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
81 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MTIF2
Additional Names:
Translation initiation factor IF-2, mitochondrial, IF-2(Mt), IF-2Mt, IF2(mt), MTIF2
Protein Accession Number:
P46199
Protein Gi Number:
223590069
Ncbi Gene Id Number:
4528
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
During the initiation of protein biosynthesis, initiationfactor-2 (IF-2) promotes the binding of the initiator tRNA to thesmall subunit of the ribosome in a GTP-dependent manner.Prokaryotic IF-2 is a single polypeptide, while eukaryoticcytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine livermitochondria contain IF-2(mt), an 85-kD monomeric protein that isequivalent to prokaryotic IF-2. The predicted 727-amino acid humanprotein contains a 29-amino acid presequence. Human IF-2(mt) shares32 to 38% amino acid sequence identity with yeast IF-2(mt) andseveral prokaryotic IF-2s, with the greatest degree of conservationin the G domains of the proteins. Two transcript variants encodingthe same protein have been found for this gene. [provided byRefSeq].
Background Reference 1:
Dick, D.M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. (2010) In press :
Background Reference 2:
Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)
Background Reference 3:
Miura, E., et al. Plant Cell 19(4):1313-1328(2007)
Background Reference 4:
Bouwmeester, T., et al. Nat. Cell Biol. 6(2):97-105(2004)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-834

List Size:
400 ul

List Price:

$495.00

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