MTMR14 Antibody

CATALOG NUMBER: 59-225

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This MTMR14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human MTMR14.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
72 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
MTMR14
Additional Names:
Myotubularin-related protein 14, 313-, HCV NS5A-transactivated protein 4 splice variant A-binding protein 1, NS5ATP4ABP1, hJumpy, MTMR14, C3orf29
Protein Accession Number:
Q8NCE2
Protein Gi Number:
118568016
Ncbi Gene Id Number:
64419
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a myotubularin-related protein. Theencoded protein is a phosphoinositide phosphatase that specificallydephosphorylates phosphatidylinositol 3,5-biphosphate andphosphatidylinositol 3-phosphate. Mutations in this gene arecorrelated with autosomal dominant centronuclear myopathy.Alternate splicing results in multiple transcript variants. Apseudogene of this gene is found on chromosome 18.
Background Reference 1:
Gibbs, E.M., et al. Autophagy 6(6):819-820(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Vergne, I., et al. EMBO J. 28(15):2244-2258(2009)
Background Reference 4:
Tosch, V., et al. Hum. Mol. Genet. 15(21):3098-3106(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-225

List Size:
400 ul

List Price:

$495.00

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